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GM 12580426 Fuel Injector: Applications, Specs, and Replacement Considerations

by flippancy 12 Aug 2026

The GM 12580426 is a port fuel injector used in many General Motors vehicles. If one of yours is due for replacement, this guide covers the specs that matter, the checks to run before you order, and the steps that keep the installation safe.

The source reference classifies it as a high-impedance, EV6-style injector with a nominal resistance of approximately 12 ohms, often associated with GM 2.4L and 3.6L engines. That association is a starting point, not a fitment guarantee — verify against your VIN and model year before you buy.

GM 12580426 specifications at a glance

The table pulls together the figures documented for this part. The pressure value applies to returnless fuel systems; the exact operating pressure in your vehicle depends on the application.

Specification Value
Part number GM 12580426
Injector type Port fuel injector
Electrical style High-impedance, EV6-style
Nominal resistance Approximately 12 ohms (Ω)
Typical operating pressure Around 43.5 psi for returnless systems; exact pressure depends on the application
Common engine association GM 2.4L and 3.6L engines
Fitment verification Vehicle VIN and model year

Why the electrical profile matters

The 12 Ω resistance figure is what places this injector in the high-impedance, EV6-style category. When you cross-reference a replacement, match that electrical profile along with the connector shape and mounting points — a similar-looking part can still be incompatible.

What to verify before you order

Start with the vehicle year, make, model, engine or drivetrain, and the original equipment number printed on the removed part. Then match connector shape, mounting points, dimensions, and left or right position where applicable. Read the seller's fitment notes and compare the original part before installation.

  • Record the VIN and exact trim level.
  • Compare the OE or interchange number and connector layout.
  • Check whether the part is front/rear, left/right, or a complete set.
  • Inspect nearby components that could cause the same symptom.

The last bullet matters: a nearby component can mimic a failed injector, so confirm the real fault before you spend.

Use the OE number as your anchor

The number printed on the removed part is your most reliable reference. Two injectors can look nearly identical while serving different applications, and connector layouts change across model years. Match the OE or interchange number first, then use photos and fitment notes as the secondary check.

Compare listings before you commit

Once the OE number is in hand, browse before you buy. The Air & Fuel Delivery collection gathers KOEEP's fuel-system parts in one place, so you can line up injector options for your platform and check fitment notes side by side.

If your GM vehicle runs a V8

The 12580426 is associated with 2.4L and 3.6L engines. If your GM truck or SUV runs a V8 instead, the catalog carries dedicated listings — for example, a fuel injector compatible with GMC, Chevrolet and Cadillac 99-07 V8 6.0L, 5.3L and 4.8L engines.

Working on a 5.3L V8? KOEEP lists a set of 8 USA fuel OEM injectors for the 2007-09 Chevy Chevrolet GMC 5.3L V8, part 12594512, which covers all eight cylinders in a single order.

For the police-package sedan, there is a set of 8 fuel injectors, part 12639221, for the 2011–2017 Chevrolet Caprice PPV 6.0L V8. Same idea, different engine and body.

One number, one application

That is the pattern across the catalog: injector part numbers map to specific engines, years, and trims — which is why the guide pushes you toward the VIN and OE number over a visual match.

Symptoms and diagnostics: confirm before you replace

The source guide treats symptom recognition as a diagnostic job, not a guessing game. Scan the diagnostic codes and inspect nearby components that could cause the same symptom before you order anything.

After installation, test the repair before the vehicle goes back into service. If a warning light remains on, scan the relevant codes again and verify the repair instead of replacing additional parts at random.

Installation checklist

Disconnect power when the procedure requires it, support the vehicle correctly, and follow the workshop manual for torque values and calibration steps. Fuel systems punish shortcuts, so give those steps their due.

  • Clean mating surfaces before assembly.
  • Route wiring away from heat and moving parts.
  • Use new O-rings and seals when you replace the injector.
  • Inspect the fuel rail for debris while it is open.
  • Test the repair before returning the vehicle to service.

New O-rings and seals are part of the job, not an upsell — the guide calls for them at replacement. While you have access, inspect the fuel rail for debris; anything left in there ends up in a fresh injector.

How to choose the right replacement

Prioritize verified compatibility, material quality, warranty coverage, and clear product photos. Photos let you compare the connector and body against your original before the part ever reaches your door.

For safety-critical systems such as brakes, steering, sensors, and fuel delivery, use the vehicle-specific specification rather than a universal substitute. Aftermarket replacements for the 12580426 exist from multiple brands, but OEM and OE-equivalent parts are recommended for reliable fuel delivery.

Keep the original part until the new component has been test-fitted and confirmed. If anything needs to go back, the reference part stays in your hands.

Related guides on KOEEP

Servicing imports as well? The 23250-31020 injector guide for the Lexus IS250 2.5L V6 (2006–2015) applies the same verify-first method. For GM 2.2L and 2.4L Ecotec engines, the 12582704 fuel injector master guide covers specs, DTC mapping, and OEM cross-reference.

And if your weekend happens off-road, the 0455124 fuel injector guide for Polaris machines covers the Sportsman, Outlaw 110, and RZR 170 across 2016–2025.

The one rule to remember: order from the VIN, the trim level, and the OE number on the removed part — never from the listing photo alone.

Need help matching the 12580426 to your vehicle?

Send your VIN and the OE number from the removed part, and KOEEP will check the match before you order. Prefer to browse first? Start with the Air & Fuel Delivery collection.

Request a fitment quote

Frequently asked questions

Will the GM 12580426 fit every GM vehicle?

No. It is often associated with GM 2.4L and 3.6L engines, but fitment depends on model year, engine, body style, and connector differences. Verify the complete range against your VIN before ordering.

What resistance should this injector measure?

Approximately 12 ohms (Ω). That nominal resistance is why it is classified as a high-impedance, EV6-style injector — use that electrical profile when you cross-reference.

What fuel pressure does it run at?

Around 43.5 psi for returnless fuel systems. The exact pressure depends on the vehicle application, so treat that figure as a reference point rather than a universal setting.

Should I buy a single injector or a set?

Check what your application calls for — the pre-order checklist tells you to confirm whether the part is a single unit, a left/right pair, or a complete set. KOEEP stocks eight-piece sets for V8 platforms like the 5.3L and the Caprice PPV 6.0L.

What else should I replace along with it?

New O-rings and seals, plus an inspection of the fuel rail for debris. Both are listed in the installation checklist for this part.

The warning light stayed on after the swap — now what?

Recheck power, grounds, fasteners, alignment, and diagnostic codes, then compare the installed part with the removed component. Verify the repair instead of replacing more parts at random.

How do I get a fitment check before buying?
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